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Nat Genet 2013

The 2023 review by Shin and colleagues at Chung-Ang University in International Wound Journal is unusually direct about the delivery problem

Collectively, our study demonstrates that engineered bispecific antibodies targeting drug-modified KRAS G12C neoantigens enhance MHC presentation and elicit potent, selective T cell-mediated cytotoxicity across HLA supertypes

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ATP7A facilitates the efflux of Cu+ from the intestinal epithelium into the circulation whereas ATP7B stores excess Cu+ in intracellular vesicles to maintain normal homeostasis (31)